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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare professionals to choose the appropriate test first time. Patients benefit from faster diagnosis and more targeted treatment. Clinicians benefit from improved stewardship for antibiotics. Labs save money while increasing efficiency. The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes with semiquantitative results that take less than an hour. Respiratory The burning of biomass, like wood, plants and other organic materials produces gaseous pollution and fine particles that negatively affect the respiratory system. Climate change may increase the negative effects of forest fires on human health. In the United States wildfire smoke is associated with hospitalizations caused by respiratory illnesses like asthma, COPD, and lung cancer. This type of air pollution also increases the risk of cardiovascular disease and is a major contributor to the burden on disease among the most vulnerable populations. In the COVID-19 epidemic, many communities were exposed to harmful levels of air pollution due to wildfires. The response of public health has been limited to a public education campaign about symptom management. This knowledge gap is alarming due to the fact that smoking cigarettes and other causes of poor quality air can lead to health issues. Researchers are now looking at the best methods to safeguard the public's health in future events similar to this. NIH is funding research on this critical public health problem through the BLUE CORAL study as well as its successor, FIRE CORAL. First time that a prospective study is conducted, it will evaluate long-term outcomes of exposure to smoke from wildfires and other sources. FIRE CORAL enrolls adults who are hospitalized for COVID-19 index episodes and who speak English or Spanish, but are not pregnant. The FIRE CORAL protocol includes a series of tests in-person that objectively measure pulmonary function testing and lung imaging and functional assessments. Smoke and other particles can cause or worsen chronic respiratory conditions such as emphysema, COPD, and pneumonia. There are a variety of steps that can be taken to avoid or lessen the negative health effects of exposure to smoke, such as avoidance of outdoor activities whenever possible and wearing the EPA's “N95” mask that is designed to catch fine particles. Smoking can cause irritation to the throat and eyes, and cause a runny nose. To minimize symptoms, drink lots of water and take medication to reduce inflammation, such corticosteroids. Bloodstream The bloodstream is your first line of defense against germs that invade your system. Special cells called dendritic cells are akin to your fire department's call center. they collect the antigens (molecules that trigger an immune response) from invaders and release proteins to signal other white blood cells to come fight them. Circulating total white blood cell counts, differentials and band cells were elevated following firefighters' fire-fighting shifts, compared with levels following physical exertion without fire-fighting. Skin As the wildfires in California produced smoke and dust into the air this past winter and fall dermatologists were concerned about how this could affect the skin of those who were exposed to it. Maria Wei, a graduate student at University of California, Irvine, is studying how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22. The research of Wei shows that the temperature of the skin changes depending on the length of time that the body is exposed to flames. It can take as long as two hours for the skin to reach its flash point—the point at which it burns and then turns to ash. It is important to avoid staying near a fire pit or campfire and wear protective clothing if you're going outside in a humid or hot day. Forest fires will continue to happen, despite the precautions implemented to reduce the risk of wildfire pollution. Wei predicts that the number of people suffering from the consequences of wildfires will increase as climate change causes more and more forests to burn. This means that more people will have to wear long sleeves and hats and thick moisturizers. It's also important to know that the atopic dermatitis (itchy skin) that a lot of people suffer from is often exacerbated by air pollution from wildfires. The particles in smoke can clog up pores, making atopic skin worse. Atopic dermatitis can also make people more sensitive to UV light. This is often exacerbated by smoke from wildfires. This makes people more likely to go to tanning salons, and may cause people to tan less protection than they should. While a fire and ice facial may reduce the effects of atopic dermatitis, it's not recommended for those with an open wound or a rash on their face. This treatment is not recommended for people with active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' premiere membership MedSpa offers a thorough and effective facial that bridges the gap between a mild facial and a peel, without requiring any downtime. It's designed to rejuvenate the skin, alleviate the appearance of rosacea, lessen acne scarring, diminish wrinkles, and promote cellular renewal. It's an incredible treatment to give yourself an energizing glow. Infections The human body is a complicated system of organs and tissues that work to shield us from infection. Infections are caused by microscopic organisms such as viruses, bacteria, parasites and fungus that invade healthy cells and cause them to reproduce out of control. When this occurs, your immune system may react with symptoms of illness. These symptoms could be anything from a snoring nose to a stomach that is upset as well as swelling of lymph glands or a rash. The type of infection and its location can affect the severity of your symptoms. Infections can spread in various ways, but the most common is through droplets in the air that remain after coughing or sniffling. This is how bacterial illnesses like strep, tuberculosis and meningococcal illness, as well as viral infections, such as the common cold and influenza, spread. Some bacterial infections, such as skin infections and sexually transmitted infections (STIs) such as gonorrhea and Chlamydia, can be transmitted through direct contact with infected tissue or mucous membranes as well as indirect contact with surfaces that are contaminated. Certain bacterial infections are transmitted by insects such as ticks, fleas, or mosquitoes. Viruses and some parasites are small enough to penetrate your bloodstream and infect your cells, which leads to serious illnesses like the common cold or AIDS. Fungi can cause skin conditions like athlete's feet and ringworm and others can infect the respiratory system and the nervous system. The BioFire PN Panel utilizes our revolutionary FilmArray technology to detect a comprehensive list of pathogens responsible for upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit comes with the reagent pouch which stores all the necessary chemicals to perform reverse transcription PCR, nested multiplex testing and detection on a single machine. bioethanol fire fireplacesandstove.com 's a simple-to-use tool to help clinicians syndromicly identify and treat patients suffering from various respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high complexity labs.